![]() ![]() However, the causal link between vitamin D and many extra-skeletal outcomes remains unclear. ![]() There is consensus that severe vitamin D deficiency (serum 25-hydroxyvitamin D (25OHD) concentration 50 nmol/l for optimal bone health in older adults. Preclinical and observational data suggest that the vitamin D endocrine system has a wide spectrum of skeletal and extra-skeletal activities. Vitamin D supplementation can prevent and cure nutritional rickets in infants and children. ![]()
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